Jeovany A. Mejía-Mejía, Faculty of Health Sciences, Universidad del Sinú, Cartagena de Indias, Colombia
Andrey Moreno-Torres, National Cancer Institute of Colombia, Bogotá, Colombia
Johana M. Mejía-Mejía, Department of Anesthesiology, Hospital Universitario de Puebla (BUAP), Puebla, Pue, Mexico
Marco A. Morales-Osorio, Faculty of Health, School of Kinesiology, Universidad Santo Tomás, Santiago, Chile

Chondroblastic osteosarcoma of the paranasal sinuses presents itself as a challenge in head-and-neck cancer. A 25-year-old woman presented with a rapidly growing mass on the right side of her face, accompanied by recurrent episodes of nosebleeds and vision impairment. The histopathological diagnosis was chondroblastic osteosarcoma with a small cell component in a hemangiopericytic pattern. Treatment with chemotherapy was administered, and subsequent surgical management involved partial resection of the affected area, maxilloethmoidectomy, and use of a vertical rectus abdominis myocutaneous flap.