Alejandro López-Landa, Department of Neurophysiology, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico
Sergio Vidal-Michaca, Department of Neurophysiology, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico
Carmen Rubio, Department of Neurophysiology, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico
Martha L. Tena-Suck, Pathology Service, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico

Craniopharyngioma (CP) is a rare benign brain tumor. Lipid thrombosis and thalamic infarction are uncommon complications following CP surgery. We report a rare autopsy case of CP that presented with difficult-to-control diabetes insipidus and thalamic infarction after surgery. Macroscopic examination of the brain revealed hemorrhagic infarcts in the thalamus and histologically showed necrosis and lipid droplets in the thalamic vessels and neurons. No tumor was observed. This case report highlights the possible occurrence of intracranial thalamic infarction due to surgery-induced vasculopathy following CP resection.