Radiotherapy in eccrine porocarcinoma: literature review




Plácido D. Esqueda-Guerrero, Departamento Clínico de Radioterapia, Unidad Médica de Alta Especialidad Nº 1, Centro Médico Nacional Bajío, IMSS, León, Gto., México
Yicel Bautista-Hernández, Unidad de Radioterapia, Servicio de Oncología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México


Introduction: The eccrine porocarcinoma is a pathology originated in the ductal intradermic portion of the sweat gland, with an incidence of 0.2 per million of habitants. It is more frequently in women above 70 years old and mostly lower extremities. The etiology is not known precisely, nevertheless it is been associated to several pathologies. Clinical Case: Female, 79 years old, with a dermal injury on the outer side of the left leg, from which a biopsy was performed (11/21/14) resulting an eccrine porocarcinoma, surgical treatment was offered as first option, but it was rejected by the patient, so she was treated with external beam radiotherapy (April–May 2015), during the treatment, skin toxicity grade 1 was shown. Follow up of 24 months
with adequate evolution. Discussion: This is a pathology that can be presented de novo or secondary to an eccrine poroma. There is no consensus for their treatment in the whole world, however the most used treatment is by surgical resection as a single modality. In the clinical case presented, the treatment with radical external beam radiotherapy is explored as a management option, with similar results in disease control compared to the surgical treatment. Conclusions: Radical external beam radiotherapy can be a option to treat this pathology, achieving local and remote control of the disease, however further studies are required to support what we have previously discussed.



Keywords: Radiotherapy. Eccrine porocarcinoma. Malignant eccrine poroma.





ESP / ENG