New insights about organoids as model of study for breast cancer research

New insights about organoids as model of study for breast cancer research

Ignacio U. Macías-Paz 1, Alejandro Rivera-Arenas 1, Elizabeth Reyna-Beltrán 1, Alejandra Tavera-Tapia 1

1 Dr. Alberto Romo Caballero´s School of Medicine, Research Division, Universidad Autónoma de Tamaulipas, Tampico, Tamps., Mexico

Ignacio U. Macías-Paz, Alejandro Rivera-Arenas, Elizabeth Reyna-Beltrán, Alejandra Tavera-Tapia

La información completa de afiliaciones y autor de correspondencia está disponible en la versión original en PDF.

*Correspondencia: Alejandra Tavera-Tapia, Email no disponible

Resumen

Although the current advances in breast cancer (BC) research, it is still one of the leading causes of death from neoplastic diseases in women and causes millions of new cases worldwide. It has become evident that traditional methods used for BC research have serious limitations. We have reviewed the most recent findings in the application of Breast Cancer Organoids (BCOs) to explore extremely rare BC forms, BC hallmarks, biobanks, and interaction with the microenvironment. Moreover, we explored the importance of its applicability in clinical trials, drug screening, and personalized medicine.

Palabras clave:  Organoids. Breast cancer. Clinical trials. Personalized medicine.

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