Evaluation of sialic acid concentrations and its association with the use of hormonal contraceptives
Andrea G. Rodríguez-López 1, Mónica L. Córdova-Serrano 2, Ana L. González-Bolaños 2, Karen B. Téllez-Blanco 2, Laura S. Marín-Jaureguí 3, Ma. José Santoyo-Treviño 4, Aida C. Hernández-Arteaga 4
1 Physical-Mathematical Department, Universidad Autónoma de San Luis Potosí, S.L.P., Mexico; 2 Faculty of Chemical Sciences, Universidad Autónoma de San Luis Potosí, S.L.P., Mexico; 3 Division of Molecular and Translational Medicine, Research Center of Health Science and Biomedicine, Universidad Autónoma de San Luis Potosí, S.L.P., Mexico; 4 Coordination for Innovation and Application of Science and Technology. Universidad Autónoma de San Luis Potosí, S.L.P., Mexico
Andrea G. Rodríguez-López, Mónica L. Córdova-Serrano, Ana L. González-Bolaños, Karen B. Téllez-Blanco, Laura S. Marín-Jaureguí, Ma. José Santoyo-Treviño, Aida C. Hernández-Arteaga
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*Correspondencia: Aida C. Hernández-Arteaga, Email no disponible
Resumen
Objective: To evaluate the relationship between the use of HC and the concentration of Sialic acid (CSA) detected in the saliva of 120 women from San Luís Potosí, Mexico. Methods: Three groups were evaluated: control group, HC intake shorter than 4 years, and HC intake longer than 4 years. A questionnaire was applied, anthropometric measures were taken, and collection of saliva samples was carried out. The samples were analyzed with Raman-SERS, for which silver nanoparticles were synthesized, and the measurement of SA was held. Results: The concentrations were divided into three SA groups: normal (≤ 4 mg/dL), risk (> 4-7 mg/dL), and altered (> 7 mg/dL). The maximum CSA was detected, which was 9.2 mg/dL. All the volunteers who used the intrauterine system (IUS) and most of the ones who used the pills and subdermal implant (SI) presented risk and altered concentrations. Conclusions: That there is an association between the HC and the CSA, presenting a higher concentration, those volunteers who used IUS, contraceptive pills, and SI.
